International Journal of Green Pharmacy  
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Year : 2008  |  Volume : 2  |  Issue : 4  |  Page : 188-193

Herbal drug usage with modern medicine 1: Case study of an enzyme inducer, St John's Wort - Some perspectives


Development of Global Drug, ClinTec (India) International Pvt. Ltd, 3rd Floor, 'A' Wing, Divyasree Chambers, Langford Road, Bangalore - 560 025, India

Correspondence Address:
Nuggehally R Srinivas
Development of Global Drug, ClinTec (India) International Pvt. Ltd, 3rd Floor, 'A' Wing, Divyasree Chambers, Langford Road, Bangalore-560 025
India
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DOI: 10.4103/0973-8258.44729

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While the usage of herbal medicines continues to be on the rise, it brings along an imminent risk of drug-drug interaction with scores of modern day medicine(s). The focus of this article is to provide an overview of a potential drug-drug interaction resulting, due to induction of cytochrome P450 enzyme(s) and/or transporters, from the use of a popular herbal product known as St. John's Wort (SJW) with modern day medicines. Also, it provides some perspectives and considerations in rationalizing the use of SJW.


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