| ORIGINAL ARTICLE |
|
| Year : 2009 | Volume
: 3
| Issue : 3 | Page : 230-233 |
|
|
Antifertility activity of ethanolic extracts of Plumbago indica and Aerva lanata on albino rats
RV Savadi, KR Alagawadi
Department of Phytochemistry, K.L.E's College of Pharmacy, Belgaum, Karnataka, India
Correspondence Address:
R V Savadi
Department of Phytochemistry, K.L.E's College of Pharmacy, Belgaum, Karnataka
India
  | 2 |
DOI: 10.4103/0973-8258.56281
|
|
|
The ethanolic extract of roots of Plumbago indica and aerial parts of Aerva lanata were evaluated for antifertility activity using anti-implantation, abortificient, and motility of rat spermatozoa (in-vitro) models. The anti-implantation effect seems to be depending on the dose as well as the initiation of treatment on specific days of pregnancy. P. indica has showed percentage pre-implantation loss of 40% and 50% against control at the doses of 200 and 400 mg/kg b/w. Percentage pregnancy failure among treated groups was 60% and 70% at the doses of 200 and 400 mg/kg b/w, whereas A. lanata has shown pre-implantation loss of 20% and 30% against control at the dose of 200 and 400 mg/kg b/w, respectively. Percentage pregnancy failure among treated groups was 30% and 40% at the dose of 200 and 400 mg/kg b/w, respectively. Both P. indica and A. lanata at a concentration of 10% have shown no motility of rat spermatozoa within 60 seconds. |
|
|
|
| [FULL TEXT] [PDF]* |
|
 |
|
