http://www.greenpharmacy.info/currentissue.asp Table of Contents:Int J Green Pharm 2010 - 4(2) International Journal of Green Pharmacy Medknow Publications0973-8258 Viana Tira-Picos Joseph M.F Nogueira Adebayo A Gbolade Original Article International Journal of Green Pharmacy 2010 4(2):67-70doi:10.4103/0973-8258.63877 International Journal of Green Pharmacy 10.4103/0973-8258.63877 http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=67;epage=70;aulast=Tira-Picos http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=67;epage=70;aulast=Tira-Picos42 67 70 http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=67;epage=70;aulast=Tira-Picos Viana Tira-Picos, Joseph M.F Nogueira, Adebayo A Gbolade

International Journal of Green Pharmacy 2010 4(2):67-70

Hydro-distilled essential oils from leaves of Piliostigma thonningii and P. reticulatum (Caesalpiniaceae) were studied by combined gas chromatography and gas chromatography-mass spectrometry for the first time. Both qualitative and quantitative differences existed in the composition of the two oils. While P. thonningii oil is composed of sesquiterpenes and monoterpene hydrocarbons, monoterpenes and sesquiterpene hydrocarbons represented the chief class of terpenoids in P. reticulatum. Major constituents in P. reticulatum leaf oil were γ-muurolene (10.3%), α-pinene (9.4%), tricyclene (7.2%), δ-cadinene (5.6%), α-terpineol (5.3%) and β-caryophyllene (4.2%). However, the sesquiterpene-rich P. thonningii oil was characterized by β-myrcene (13.3 %), limonene (8.6%), α-pinene (7.6%), β-caryophyllene (7.1%), γ-muurolene (6.1%), caryophyllene oxide (5.2%) and spathulenol (4.0%).]]> http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=67;epage=70;aulast=Tira-Picos TB Lima A Suja OS Jisa S Sathyanarayanan KS Remya Original Article International Journal of Green Pharmacy 2010 4(2):71-74doi:10.4103/0973-8258.63878 International Journal of Green Pharmacy 10.4103/0973-8258.63878 http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=71;epage=74;aulast=Lima http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=71;epage=74;aulast=Lima42 71 74 http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=71;epage=74;aulast=Lima TB Lima, A Suja, OS Jisa, S Sathyanarayanan, KS Remya

International Journal of Green Pharmacy 2010 4(2):71-74

Liver toxicity is a major health problem of worldwide proportions. Herbal medicines derived from plant extracts are being increasingly utilized to treat a wide variety of clinical diseases. In the present study, LIV-first (16.3 mg/kg, p.o.) was used to screen the hepatoprotective activity. Hepatotoxicity was induced in experimental animals by administration of carbon tetrachloride (CCl 4 ) (1 ml/kg, i.p). Silymarin (25 mg/kg,p.o.) was used as the standard. Biochemical parameters like serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), alkaline phosphatase (ALP) and serum bilirubin were measured. Cytotoxicity of CCl 4 was estimated by quantitating the release of malondialdehyde. The activity of tissue antioxidant enzymes namely superoxide dismutase, catalase and the level of total protein and glutathione were also measured. Histopathological evaluation of liver sections was also done. CCl 4 administration in rats elevated the levels of SGPT, SGOT, ALP and bilirubin. Administration of LIV-first significantly ( P<0.01) prevented this increase. The activity of anti-oxidant enzymes in carbon tetrachloride CCl 4 -treated group was decreased and these enzyme levels were significantly ( P<0.05) increased in LIV-first-treated groups. Histopathological studies revealed that the concurrent administration of CCl 4 with the extract exhibited protection of the liver tissue, which further evidenced the above results. The study confirmed the hepatoprotective activity of LIV-first, which may be attributed to its antioxidant property.]]> http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=71;epage=74;aulast=Lima A Umamaheswari A Nuni R Shreevidya Original Article International Journal of Green Pharmacy 2010 4(2):75-78doi:10.4103/0973-8258.63879 International Journal of Green Pharmacy 10.4103/0973-8258.63879 http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=75;epage=78;aulast=Umamaheswari http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=75;epage=78;aulast=Umamaheswari42 75 78 http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=75;epage=78;aulast=Umamaheswari A Umamaheswari, A Nuni, R Shreevidya

International Journal of Green Pharmacy 2010 4(2):75-78

The aim of the present study was to evaluate the qualitative analysis of phytochemicals and antimicrobial activity of various solvent extracts of Boerhaavia diffusa L. (Family: Nyctaginaceae) leaves. The antimicrobial activity of different solvent extracts of B. diffusa L. leaves were tested against the Gram-positive and Gram-negative bacterial strains by observing the zone of inhibition. The Gram-positive bacteria used in the test were Staphylococcus aureus, Bacillus subtilis, Streptococcus faecalis and Micrococcus luteus, and the Gram-negative bacteria were Escherichia coli, Pseudomonas aeruginosa, Salmonella typhii, Klebsiella pneumoniae, Proteus vulgaris, Serratia marcescens, Shigella flexneri and Vibrio cholerae. It was observed that ethanol, methanol, chloroform, ethylacetate and aqueous extracts showed activity against Gram-positive and Gram-negative bacteria. The ethanol extract of B. diffusa L. leaves showed more activity against Gram-positive (e.g. S. aureus, zone of diameter 11 mm) and Gram-negative bacteria (e.g. E. coli, zone of diameter 9 mm) when compared to other solvent extracts except V. cholerae. The results confirmed the presence of antibacterial activity of B. diffusa L. leaves extract against various human pathogenic bacteria.]]> http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=75;epage=78;aulast=Umamaheswari SR Badhe RV Badhe MM Ghaisas VV Chopade AD Deshpande Original Article International Journal of Green Pharmacy 2010 4(2):79-82doi:10.4103/0973-8258.63880 International Journal of Green Pharmacy 10.4103/0973-8258.63880 http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=79;epage=82;aulast=Badhe http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=79;epage=82;aulast=Badhe42 79 82 http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=79;epage=82;aulast=Badhe SR Badhe, RV Badhe, MM Ghaisas, VV Chopade, AD Deshpande

International Journal of Green Pharmacy 2010 4(2):79-82

The present study was designed to screen antidepressant activity of Anacyclus pyrethrum (AP) root extract. An experiment was designed by different method such as Locomotor activity, Haloperidol-induced catalepsy, Forced swim test (FST), Tail suspension test (TST), Clonidine-induced hypothermia and Reserpine-induced hypothermia on Swiss male albino mice. Standard root extract of Anacyclus pyrethrum (AP root extract) showed an increase in ambulatory behaviour indicating a stimulant effect of the photoactometer. AP root extract produces a significant antidepressant effect in both FST and TST as they reduced the immobility. AP root extract was found to be effective in reversing hypothermia produced by clonidine and reserpine. In our study, we found that AP root extract inhibited haloperidol-induced catalepsy. These study suggest that AP root extract might produce antidepressant effect by interaction with adrenergic and dopamine receptor thereby increasing the level of noradrenaline and dopamine in brains of mice.]]> http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=79;epage=82;aulast=Badhe PV Habbu KM Mahadevan RA Shastry SR Chilakwad Original Article International Journal of Green Pharmacy 2010 4(2):83-89doi:10.4103/0973-8258.63881 International Journal of Green Pharmacy 10.4103/0973-8258.63881 http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=83;epage=89;aulast=Habbu http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=83;epage=89;aulast=Habbu42 83 89 http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=83;epage=89;aulast=Habbu PV Habbu, KM Mahadevan, RA Shastry, SR Chilakwad

International Journal of Green Pharmacy 2010 4(2):83-89

Several 'rasayana' herbs that are enlisted in Indian system of medicine have been in use for the treatment of age-related neurodegenerative disorders including Alzheimer's disease (AD). Roots of Argyreia speciosa are used in several Ayurvedic preparations as brain tonic and nervine tonic. The present work was undertaken to justify the traditional claim of the plant as nootropic and antiamnesic agent in mice. The ethyl acetate and ethanolic fractions (EtAS) of roots were selected for the study. Exteroceptive behavioural models such as elevated plus maze and Water maze were used to assess the short-term memory, whereas, scopolamine and natural ageing- induced amnesia served as interoceptive models. The whole brain acetyl cholinesterase activity was measured to assess the effect of A. speciosa on the central cholinergic system. Scopolamine (0.4 mg/kg, i.p.) increased the transfer latency significantly ( P<0.01) in young mice on the first and second day as compared to control indicating the impairment of memory. Pretreatment with EAAS (100 and 200 mg/kg, p.o.) significantly ( P<0.01) attenuated scopolamine and ageing-induced amnesia. Escape latency time was recorded in the water maze model as an index of acquisition, and trials were conducted for 4 days. The mean time spent in target quadrant (TSTQ) during retrieval trial on fifth day was taken as the index of retrieval (memory). EAAS (100 and 200 mg/kg, p.o.) administered before the training trial (from day 1 to day 4), significantly ( P<0.01) attenuated scopolamine and ageing-induced decrease in TSTQ during the retrieval test on the fifth day. EAAS (100 and 200 mg/kg, p.o.) significantly produced reduction in whole brain acetyl cholinesterase (AChE) activity of both young and aged mice thus exhibiting anti-AChE activity in whole brain homogenate compared to Piracetam, scopolamine and control groups of mice. The results indicate that A. speciosa has significant nootropic and antiamnesic activity, justifying its traditional use in Ayurveda.]]> http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=83;epage=89;aulast=Habbu Basavaraj C Koti Purnima Ashok Original Article International Journal of Green Pharmacy 2010 4(2):90-92doi:10.4103/0973-8258.63882 International Journal of Green Pharmacy 10.4103/0973-8258.63882 http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=90;epage=92;aulast=Koti http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=90;epage=92;aulast=Koti42 90 92 http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=90;epage=92;aulast=Koti Basavaraj C Koti, Purnima Ashok

International Journal of Green Pharmacy 2010 4(2):90-92

In the present study, petroleum ether, chloroform, and alcoholic extracts of Mimusops elengi Linn. bark (200 mg/kg body weight, p. o.) were tested for diuretic activity. The animals were grouped into five of six animals each. The first group received only 0.9% sodium chloride solution (25 ml/kg body weight) and the second group received the standard drug furosemide (20 mg/kg body weight) in 0.9% sodium chloride solution. Rest of the three groups received each of extracts viz. petroleum ether, chloroform, and alcohol of M. elengi bark in a dose of 200 mg/kg body weight suspended in 0.9% sodium chloride solution (p. o). After oral administration, urine was collected and volume was recorded at 5 hours. The highest diuretic activity was presented by the alcoholic extract. Diuretic activity was not observed in chloroform and petroleum ether extracts. We observed a potent diuretic and electrolyte excretion activity in alcoholic extract of M. elengi bark.]]> http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=90;epage=92;aulast=Koti Sankhadip Bose Vivek V Byahatti Marina D'Souza Arti Bose Original Article International Journal of Green Pharmacy 2010 4(2):93-97doi:10.4103/0973-8258.63883 International Journal of Green Pharmacy 10.4103/0973-8258.63883 http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=93;epage=97;aulast=Bose http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=93;epage=97;aulast=Bose42 93 97 http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=93;epage=97;aulast=Bose Sankhadip Bose, Vivek V Byahatti, Marina D'Souza, Arti Bose

International Journal of Green Pharmacy 2010 4(2):93-97

The bark of Polyalthia longifolia is traditionally reputed to lower blood pressure, stimulate respiration and help in fever and skin diseases, diabetes, hypertension and vitiated conditions of vata and pitta. Preliminary phytochemical investigation of various extracts of the bark of Polyalthia longifolia showed the presence of flavonoids, alkaloids, steroids and carbohydrates. An attempt has been made to isolate flavonoids and perform antioxidant and antimicrobial activity of the same. We carried out DPPH radical scavenging assay, nitric oxide scavenging assay, metal chelating activity and reducing power activity in antioxidant activity. In antimicrobial activity, we used six microorganisms, which included two Gram positive, two Gram negative bacteria and two fungi. Both the isolated flavonoids exhibited a concentration-dependant free radical scavenging capacity. Isolated compounds showed promising results against various micro-organisms in comparison with standard drugs (Penicillin, Gentamicin and Ketoconazol).]]> http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=93;epage=97;aulast=Bose Yogesh V Ushir Anil U Tatiya Sanjay J Surana Ulhas K Patil Original Article International Journal of Green Pharmacy 2010 4(2):98-101doi:10.4103/0973-8258.63884 International Journal of Green Pharmacy 10.4103/0973-8258.63884 http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=98;epage=101;aulast=Ushir http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=98;epage=101;aulast=Ushir42 98 101 http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=98;epage=101;aulast=Ushir Yogesh V Ushir, Anil U Tatiya, Sanjay J Surana, Ulhas K Patil

International Journal of Green Pharmacy 2010 4(2):98-101

The essential oil from the aerial part and roots of Anisomeles indica Linn. from the Toranmal forest, Maharashtra (India), was obtained by hydrodistillation after drying and grounding of the herbal material. A total of 27 components were resolved in the essential oil by GC-MS analysis, while 18 compounds were identified comparing the recorded mass spectra with the Nist 98/Nbs 75 K GC-MS library of mass spectra. The microbiological activity of the isolated essential oils was investigated as well. It was found that the essential oil shows microbiological activity on Escherichia coli, Pseudomonas aeruginosa, Bacillus pumilus and Staphylococcus aureus with a range of minimum inhibitory concentration values extended from 31.25 to 250 &#956;g/ml. The percentage inhibition values calculated also support the minimum inhibitory concentration findings. The MBCs also performed for the same pathogens. Limonene, pinene, isobornyl acetate and eugenol can be considered as the main antimicrobial constituents in the essential oils of plants.]]> http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=98;epage=101;aulast=Ushir SK Panda D Dubey SK Dutta Original Article International Journal of Green Pharmacy 2010 4(2):102-107doi:10.4103/0973-8258.63885 International Journal of Green Pharmacy 10.4103/0973-8258.63885 http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=102;epage=107;aulast=Panda http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=102;epage=107;aulast=Panda42 102 107 http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=102;epage=107;aulast=Panda SK Panda, D Dubey, SK Dutta

International Journal of Green Pharmacy 2010 4(2):102-107

The anticandidal activity and phytochemicals of bark of Diospyros melanoxylon Roxb. (Ebenaceae) was evaluated against four species of Candida viz. C. albicans, C. krusei, C. parapsilosis and C. tropicalis. Both polar and nonpolar extracts viz. petroleum ether, ethyl acetate, ethanol, methanol and aqueous were prepared and studied for anticandidal activity using agar cup and broth dilution methods. Although all five extracts showed promising anticandidal activity against all tested Candida species, yet maximum activity was observed in ethanol extract. Minimum inhibitory concentration values for most of the extracts ranged from 0.375 to 6.0 mg/ml, while the least minimum fungicidal concentration value was observed at 3.0-6.0 mg/ml. Phytochemical analysis exhibited the presence of carbohydrates, protein and amino acids, tannin and phenolic compound, glycoside, steroid and sterols and flavonoids in different extracts. Thin layer chromatography bio-autography showed zones of inhibition 22 mm (C. parapsilosis) and 21 mm (C. tropicalis) with Rf value 0.72 for ethanol extract. These results exhibit the anticandidal activity of D. melanoxylon bark extracts, which may be useful in treatment of candidiasis. However, the active components responsible for antifungal activity need to be evaluated.]]> http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=102;epage=107;aulast=Panda Juliana B Dalmarco Eduardo M Dalmarco Janaina Koelzer Moacir G Pizzolatti Tania S Frode Original Article International Journal of Green Pharmacy 2010 4(2):108-114doi:10.4103/0973-8258.63886 International Journal of Green Pharmacy 10.4103/0973-8258.63886 http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=108;epage=114;aulast=Dalmarco http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=108;epage=114;aulast=Dalmarco42 108 114 http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=108;epage=114;aulast=Dalmarco Juliana B Dalmarco, Eduardo M Dalmarco, Janaina Koelzer, Moacir G Pizzolatti, Tania S Frode

International Journal of Green Pharmacy 2010 4(2):108-114

Lotus corniculatus (Fabaceae) is considered a forage plant utilized as food for ruminants in the south of Brazil. This herb is also actually used to treat intestinal infection in these animals. In our experiments, we evaluated the anti-bacterial activity of crude extract from L. corniculatus var. S&#947;o Gabriel were assayed against Gram-positive and Gram-negative bacterium. The crude extracted did not show any anti-bacterial activity, but the hexane fraction did on Bacillus cereus (MIC=100 &#956;g/mL) and on Enterococcus faecalis, Listeria monocytogenes, Staphylococcus aureus, Staphylococcus epidermidis, Acinetobacter calcoaceticus, and Providencia alcalifaciens (MIC=600, 800 or 1000 &#956;g/mL). The Ethyl acetate fraction (AcOEt) also showed important anti-bacterial activity on Bacillus cereus, E. faecalis, and Acinetobacter calcoaceticus (MIC=800 &#956;g/mL). The oleanolic acid isolated from hexane fraction showed the same effect on Staphylococcus aureus methycillin-resistant (MIC=100 &#956;g/mL), L. monocytogenes (MIC=25 &#956;g/mL), and Bacillus cereus (MIC=25 &#956;g/mL). Further, Kaempferitrin isolated from ethyl acetate fraction has also shown anti-bacterial activity on Shighella flexinerii (MIC=100 &#956;g/mL), Salmonella typhimurium (MIC=100 &#956;g/mL), A. calcoaceticus (MIC=100 &#956;g/mL), E. faecalis (MIC=3.9 &#956;g/mL), and Bacillus cereus (MIC=8.5 &#956;g/mL). This study suggests that L. corniculatus var. S&#947;o Gabriel have potential pharmacological property for a new anti-bacterial drug development.]]> http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=108;epage=114;aulast=Dalmarco B Dineshkumar Analava Mitra M Manjunatha Original Article International Journal of Green Pharmacy 2010 4(2):115-121doi:10.4103/0973-8258.63887 International Journal of Green Pharmacy 10.4103/0973-8258.63887 http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=115;epage=121;aulast=Dineshkumar http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=115;epage=121;aulast=Dineshkumar42 115 121 http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=115;epage=121;aulast=Dineshkumar B Dineshkumar, Analava Mitra, M Manjunatha

International Journal of Green Pharmacy 2010 4(2):115-121

In India, the prevalence of diabetes mellitus is on the increase and needs to be addressed appropriately. In this study area, herbal remedies are considered convenient for management of Type 2 diabetes with postprandial hyperglycemia due to their traditional acceptability and availability, low costs, lesser side effects. Comparative evaluation of alpha amylase inhibitory activities of selected plants extracts. Kharagpur is situated in the Midnapur West district of West Bengal in India. In this district, diabetes prevalence is comparatively high. Ten common plants in IIT Kharagpur 1 Block namely, Acalypha indica, Allium cepa, Allium sativum, Azadirachta indica, Musa sapientum, Mangifera indica, Murraya, Ocimum sanctum, Phyllanthus amarus and Tinospora cordifolia were tested for their alpha amylase inhibitory activities to establish anti-diabetic potentials. The plant extracts were prepared sequentially with petroleum ether, hexane, chloroform, ethanol and aqueous. The extracts obtained were subjected to in vitro alpha amylase inhibitory assay using starch azure as a substrate and porcine pancreatic amylase as the enzyme. Statistical difference and linear regression analysis were performed by using Graphpad prism 5 statistical software. Ethanol extracts of Mangifera indica, Azadirachta indica and petroleum ether extract of Murraya koenigii (at a concentrations 10-100&#956;g/ml) showed maximum percentage inhibition on alpha amylase activity with an IC 50 value of 37.86 &#177; 0.32&#956;g/ml, 62.99 &#177; 1.20&#956;g/ml and 59.0 &#177; 0.51&#956;g/ml respectively when compared with acarbose (IC 50 value 83.33 &#177; 0.75&#956;g/ml). The results showing that Mangifera indica, Azadirachta indica and Murraya koenigii might be effective in lowering post prandial hyperglycemia.]]> http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=115;epage=121;aulast=Dineshkumar Uma M Iyer Pallavi A Desai Shonima Venugopal Original Article International Journal of Green Pharmacy 2010 4(2):122-128doi:10.4103/0973-8258.63888 International Journal of Green Pharmacy 10.4103/0973-8258.63888 http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=122;epage=128;aulast=Iyer http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=122;epage=128;aulast=Iyer42 122 128 http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=122;epage=128;aulast=Iyer Uma M Iyer, Pallavi A Desai, Shonima Venugopal

International Journal of Green Pharmacy 2010 4(2):122-128

Many of the plant sources have excellent nutrient and non-nutrient properties which can be exploited to manage clinical conditions. The current study was undertaken to assess the impact of panchratna juice (Amla, Tulsi, Ginger, Mint and Turmeric) in the management of type 2 diabetes mellitus subjects. A total of 55 stable type 2 diabetics were enrolled from pathology laboratories and were given either fresh panchratna juice (n = 15) for 45 days or processed panchratna juice (n = 20) for 90 days and compared with diabetic controls (n = 20). Anthropometric profile, glycemic status and lipid profile were assessed on all the subjects at baseline, 45 days and 90 days. Students t test, paired t test and ANOVA were applied using Microsoft Excel. The results indicated that fresh panchratna juice or processed panchratna juice supplementation for long-term did not have any significant impact on the glycemic and lipemic status of diabetic subjects. Thus, the protective effects are lost with processing, and therefore, these plant sources should be consumed in their natural form.]]> http://www.greenpharmacy.info/article.asp?issn=0973-8258;year=2010;volume=4;issue=2;spage=122;epage=128;aulast=Iyer