Preliminary phytochemical and antibacterial investigations were carried out of the crude extracts obtained from the leaf of Adhatoda vasica, using solvents of varied polarity. The presence of phenols, tannins, alkaloids, anthraquinones, saponins, flavanoids, aminoacids and reducing sugars was indicated by the tests conducted. The effect of ethanol, petroleum ether and water extracts were tested on Staphylococcus aureus, Staphylococcus epidermidis, Bacillus subtilis, Enterococcus faecalis, Escherichia coli, Pseudomonas aeroginosa, Proteus vulgaris, Klesiella pneumoniae and Candida albicans . The minimum inhibitory concentration of the crude extracts was determined for various organisms.

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Delonix elata , Enicostemma axillare, Merremia tridentata, Mollugo cerviana and Solanum incanum are medicinal plants used in traditional Indian medicine for the treatment of various ailments. These plants were selected to evaluate their potential antibacterial activity. To determine antibacterial activity and phytochemicals in the crude extracts of five medicinal plants used in traditional Indian medicine for the treatment of various ailments like rheumatism, piles fever, skin diseases and snake bite. The antibacterial activity of organic solvent extracts of these plants were determined by disc diffusion and broth dilution techniques against gram-positive bacterial strains (Bacillus subtilis, Staphylococcus aureus) and gram-negative bacterial strains (Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa). Results revealed that the chloroform and methanol extracts of D. elata and methanol extracts of M. cerviana exhibited significant antibacterial activity against gram-positive and gram-negative strains with minimum bactericidal concentration (MBC) ranging from 1.5 to 100 mg/ml. Methanol extracts of M. tridentata exhibited activity only against gram-positive bacterial strains with MBC ranging from 12.5 to 100 mg/ml. Extracts of E. axillare and S. incanum showed activity only against B. subtilis and were not bactericidal at 100 mg/ml. The most susceptible organism to the organic extracts from all the studied plants was B. subtilis and the most resistant organism was P. aeruginosa. The presence of phytochemicals such as alkaloids, tannins, triterpenoids, steroids and glycosides in the extracts of these plants supports their traditional uses as medicinal plants for the treatment of various ailments. The present study reveals potential use of these plants for developing new antibacterial compounds against pathogenic microorganisms.

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Flavonoids are well-known for their many therapeutic and pharmaceutical effects. In this study, we tested the antibacterial activity of 11 flavonoids extracted from some medicinal plants by the agar diffusion method. Then, we measured their antioxidant activity using the DPPH (2,2'-diphenyl-1-picrylhydrazyl) radical assay and we also tested their acute toxicity effect on mice. The results showed that apigenin-7-O-glucoside was more active against the Gram-positive bacteria and quercetin was more active against the Gram-negative ones. Also, quercetin and diosmin showed the best antioxidant activity. Quercetin, apigenin-7-O-glucoside, luteolin-7-O-glucoside and luteolin-3'-O-glucuronide gave the best acute toxicity values. It can be concluded that quercetin was the most interesting compound for all the tested activities. Also, we observed that the presence or the absence of substitutions in flavonoids influenced significantly the results obtained, whereas the substitution type had a low impact.

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In an approach towards the development of ecofriendly antifungal compounds for controlling plant diseases caused by Fusarium oxysporum , different extracts of three weed plants, namely, Capparis decidua, Lantana camara and Tridax procumbens, were tested for their antifungal potential. The spore germination/spore counting technique was followed for the evaluation of the antibiotic properties of the extracts at three different concentrations. Results revealed that the free flavonoids and sterols of T. procumbens (flower) and bound flavonoids of C. decidua (fruit and stem) totally inhibited spore germination of the fungi (100%). The antifungal components from these plants could be used in developing novel fungicides (biopesticides) for the diseases caused by F. oxysporum (plant pathogen).

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To evaluate the immunomodulatory activity of the ethanolic extract of the stem bark of Bauhinia variegata Linn, to justify the traditional claim endowed upon this herbal drug as a rasayana in Ayurveda. The effect of the ethanolic extract of the stem bark of Bauhinia variegata (EBV) on the primary and secondary antibody responses was evaluated by the humoral antibody response for a specific immune response. The effect of EBV on the phagocytic activity was evaluated by the carbon clearance test and neutrophil activation was evaluated by the neutrophil adhesion test for a nonspecific immune response. The data was analysed by one-way ANOVA followed by Tukey-Kramar multiple comparison tests. On oral administration, EBV showed a significant increase in the primary and secondary humoral antibody responses, by increasing the hemagglutinating antibody titre at doses of 250 and 500mg/kg/p.o. There was a significant increase in the phagocytic index and percentage neutrophil adhesion at doses of 250 and 500mg/kg/p.o. The present study reveals that the ethanolic extract of the stem bark of Bauhinia variegata Linn holds a promise as an immunomodulatory agent, which acts probably by stimulating both the specific and nonspecific arms of immunity.

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The present study was designed to investigate the Antihyperlipidemic activity of alcoholic extract of Sphaeranthus indicus L. flower heads in atherogenic diet induced hyperlipidemia. Sphaeranthus indicus extract was administered in a dose of 500 mg/kg/day, p.o. for eight days. Marked decrease in body weight, total cholesterol, triglyceride, and low-density lipoprotein and very low density lipoprotein whereas significant increases in the level of high-density lipoprotein were obtained after treatment with Sphaeranthus indicus extract. The present work indicates that, Sphaeranthus indicus extract in a dose of 500 mg/kg/day effectively suppressed the atherogenic diet induced hyperlipidemia in rats, suggesting the potential protective role in atherosclerosis.

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In the present article, an endeavor has been made to present an overview of the comparison of Indian traditional herbal medicine in the international market. This article intends to contribute to this knowledge by giving a survey of published data regarding the microbial contamination of herbal plants, by dealing with methodological aspects and by considering the influence of different commonly used pharmaceutical preparation techniques on the microbiological status of the products. It also highlights heavy metal poisoning of these herbal products and the need for India to follow the Good Agriculture Practice (GAP) guidelines. As herbal medicinal products are complex mixtures, which originate from biological sources, great efforts are necessary to guarantee a constant and adequate quality. By carefully selecting the plant material and a standardized manufacturing process, the pattern and concentration of constituents should be kept as constant as possible, as this is a prerequisite for reproducible therapeutic results. China has successfully overcome such difficulties by modernizing its traditional medicine profession with government-sponsored GAPs. The cultivation practices offer Standard Operating Procedures for use of fertilizers, irrigation systems and disease management allied with insects and pest prevention and cure. GAPs also establish standards for noxious and harmful contaminants like heavy metals, pesticide residues and microbes in plants.

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The purpose of this study was to characterize the putative anxiolytic-like activity of an ethanolic extract prepared from the roots of Vitex negundo (VN) using the elevated plus maze (EPM) and light-dark exploration test in mice. Male mice were either treated orally with the VN extract or the positive control diazepam, respectively, 1 hour before behavioral evaluation. Oral administration of 100 and 200 mg/kg of VN extract significantly (P > 0.01) increased the percentage time spent on and the number of entries into the open arms of the EPM. The effect was comparable to that of the benzodiazepine diazepam (2 mg/kg p.o.). In light-dark exploration test, diazepam-treated rats significantly increased the time spent in light arena and decreased the duration of immobility, while VN treated rats also showed a significant (P >0.01) increase in the time spent (100 and 200 mg/kg) in light arena. Diazepam and the VN extracts do not produced any overt motor dysfunction. These results indicate that VN is an effective anxiolytic agent. In conclusion, the action of extract upon the anxiety models tested are in accord with the traditional use of VN L. and could be useful in primary medical care.

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Aqueous extract of Clerodendron glandulosum. Coleb (CG) (400 mg/kg/day) was orally administered to rats rendered hyperlipidemic chronically (by feeding high-fat diet; HL) to assess its possible lipid-lowering potential. The hyperlipidemic rats were administered CG extract by oral gavage from 30-90 days along with high fat diet. Plasma lipid profile was monitored on 30 ^th , 60 ^th and 90 ^th days to assess the effect of CG extract. Observations revealed a decrement in body weight (9.6%), plasma TC (15.63%), TG (42.99%), PL (13.91%), LDL-C (81.36%) and VLDL-C (43%) along with an increase in HDL-C (52.84%) at 90 days (after 60 days of CG extract feeding) compared to high levels at 30 days. Fecal lipid analysis revealed high content of TC, TG and PL in HL + CG group. Lipid-lowering property of the CG extract in chronic hyperlipidemic rats validates its use traditionally as a part of folklore medicine in North-eastern India, though there is no scientific evaluation to date.

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In recent times, the use of herbal products has increased tremendously in the western world as well as in developed countries. Lately, one of the outstandingly important medicinal plants, widely used therapeutically in the orient and becoming increasingly popular in the west is Bacopa monniera, a well-known nootropic. The present review summarizes our current knowledge of pharmacological actions, preclinical and clinical studies, major bioactives, reported mechanisms of actions, clinical efficacy, safety and the possibility of interactions of the herb with the conventional drugs. Simultaneously, research updates as well as avenues for further research are also mentioned concerning the plant.

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We investigated the antihyperlipidemic activity of an aqueous extract of a herbal preparation from a combination of six Indian medicinal plants. The current study was undertaken to assess the hypolipidemic, hypocholesterolemic and hypotriglyceridemic potential of the polyherbal extract using Triton WR 1339 (Tyloxapol) induced hyperlipidemia. The animals were divided into four groups'normal control, hyperlipidemic control, hyperlipidemic plus polyherbal extract and hyperlipidemic plus Lovastatin. Hyperlipidemia was induced by single intravenous injection of Triton WR 1339. Intragastric administration of polyherbal extract (500mg/kg of body weight) significantly decreased plasma cholesterol, triglyceride, non-HDL-C and phospholipids levels and increased HDL-C levels. Atherogenic index and triglyceride secretion rate were lowered in the polyherbal extract fed animals when compared to hyperlipidemic animals. Polyherbal extract exhibited quite competitive potential when compared with the reference drug Lovastatin affording a possible alternative therapeutic agent in the treatment of hyperlipidemia.

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The methanolic extract of Tylophora indica leaves was screened for hepatoprotective activity in carbon tetrachloride induced hepatotoxicity in albino rats. The degree of protection was measured by estimating biochemical parameters like Serum glutamate oxaloacetate transaminase, serum glutamate pyruvate transaminase, total protein and level of serum bilirubin (both total and direct). Hepatoprotective activity of methanolic extract at a dose of 200 mg/kg and 300 mg/kg body weight, i.p., was compared with Silymarin (25 mg/kg, i.p.) treated animals. Tylophora indica leaves (200 and 300 mg/kg) exhibited significant reduction in serum hepatic enzymes when compared to rats treated with carbon tetrachloride alone. Furthermore, histopathological studies were also done to support the study.

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The effect of oral administration of aqueous and alcohol extracts of Jasminum auriculatum Vahl (Oleaceae) flowers on calcium oxalate nephrolithiasis has been studied in male albino rats. Ethylene glycol feeding resulted in hyperoxaluria as well as increased renal excretion of calcium and phosphate. Supplementation with aqueous and alcohol extract of J. auriculatum flowers significantly reduced the elevated urinary oxalate, showing a regulatory action on endogenous oxalate synthesis. The increased deposition of stone forming constituents in the kidneys of calculogenic rats was significantly lowered by curative and preventive treatment using aqueous and alcohol extracts. The results indicate that the flowers of J. auriculatum are endowed with antiurolithiatic activity.

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Many herbal remedies individually or in combination have been recommended in various medical treatises for the cure of different diseases. The Pongamia pinnata, commonly known as 'Karanj', has been recognized in different system of traditional medicines for the treatment of different diseases and ailments of human beings. It contains several phytoconstituents belonging to category flavonoids and fixed oils. The fruits and sprouts of P. pinnata were used in folk remedies for abdominal tumours in India, the seeds for keloid tumours in Sri Lanka and a powder derived from the plant for tumours in Vietnam. In Sanskritic India, seeds were used for skin aliments. Today, the oil is used as a liniment for rheumatism. Leaves are active against Micrococcus; their juice is used for cold, cough, diarrhoea, dyspepsia, flatulence, gonorrhoea and leprosy. Roots are used for cleaning gums, teeth and ulcers. Bark is used internally for bleeding piles. Juices from the plant as well as oil are antiseptic. In the traditional systems of medicines, such as Ayurveda and Unani, the P. pinnata plant is used for anti-inflammatory, anti-plasmodial, anti-nonciceptive, anti-hyperglycaemics, anti-lipidoxidative, anti-diarrhoeal, anti-ulcer, anti-hyperammonic and antioxidant. Its oil is a source of biodiesel. It has also alternative source of energy, which is renewable, safe and non-pollutant.

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This study elucidated the physical, thermal, sorption and functional properties of a gum obtained from the stem of Cissus refescence (CRG). Scanning electron microscopy (SEM), Particle size analysis, X-ray powder diffraction (XPRD), Thermo gravimetric analysis (TGA), Differential scanning colorimetry (DSC), Fourier transmittance infra red (FTIR), and Elemental analysis were used to characterize the gum sample. Tablets were prepared by incorporating an anti asthmatic drug; theophylline. In vitro drug release was carried out in simulated gastric and intestinal conditions. Effect of gum concentration on release kinetics was evaluated. CRG had a glass transition (Tg) and melting peak of 233.5 and 270 ^o C respectively. This material showed a 10.59 % loss in weight at 195 ^o C. The sample had very strong peaks at approximately 14 ^o , 15 ^o , 23 ^o , 24 ^o , and 29 ^o 2θ degrees of 2-theta (θ) in the X-Ray Powder Diffraction pattern. Elemental analysis showed that CRG contains 44.1, 7.1, 48.5, and 0.3% Carbon, Hydrogen, Oxygen and Nitrogen respectively. Release of theophylline under simulated biologic conditions varied between 2 to 12 hours depending on the concentration of the gum used in formulation. Drug release was found to be erosion-controlled initially (i.e. in SGF), but at later stage, it became swelling -controlled (i.e. in SIF). The results obtained in this study establish the fundamental characteristics of CRG. The matrices were pH sensitive and can potentially be used for intestinal drug delivery.

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The development of anthelmintic resistance and the high cost of conventional anthelmintic drugs led to the evaluation of medicinal plants as an alternative source of anthelmintics. In the current study, in-vitro experiments were conducted to determine the possible anthelmintic effects of crude aqueous and hydroalcoholic extracts of the leaves of Chenopodium ambrosioides, Lawsonia inermis and seeds of Jatropha curcas, on eggs and adult Haemonchus contortus. Both extracts of C. ambrosioides and J. curcas inhibited the hatching of eggs at a concentration less than or equal to 2mg/ml, while the effect of L. inermis was not dose-dependent and did not inhibit the hatching of eggs of H. contortus, significantly, at all tested concentrations. Based on their ED ₅₀ , the two most potent extracts using egg hatch assay were the hydroalcoholic extract of C. ambrosioides (0.09mg/ml) and the aqueous extract of J. curcas (0.1mg/ml) in a decreasing order of potency. With regard to the effect of extracts on the survival of adult parasites, extracts from C. ambrosioides have shown a moderate effect, while J. curcas and L. inermis have shown no statistically significant effect on the survival of adult parasites at the concentrations tested, and the few mortality cases recorded were not dose-dependent ( P < 0.05). The overall findings of the present study have shown that C. ambrosioides and J. curcas contain possible anthelmintic compounds and further evaluation of these plants should be carried out.

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Gloriosa supberba (family: Liliaceae) is widely used as a medicinal plant, and the alkaloids from the plant (Colchicines and Gloriosine) are used in the treatment of gout and rheumatism. We evaluated the analgesic and anti-inflammatory activities of hydroalcoholic extract (50% v/v) of dried aerial parts of G. superba. The analgesic activity of the extract was evaluated by using Eddy's hot plate method and acetic acid-induced writhing method. The anti-inflammatory activity was evaluated by using the cotton wool granuloma model and the carrageenan-induced paw edema model. The percentage inhibitions of writhes or percentage protection were found to be 64.09%, 78.56% and 81.45% for extract at a dose 100, 200 and 400 mg/kg body weight, respectively, in the acetic acid-induced writhing method (P <0.01) when compared with control. The percentage increase in reaction time at 90 minutes were 21.02%, 79.96% and 158.05% for extract at a dose of 100, 200 and 400 mg/kg body weight, respectively, in Eddy's hot plate method (P <0.01) when compared with control. The percentage inhibition of paw edema was increased with time and gave maximum effect at 2 hours, then declined in case of standard extract 400 mg/kg body weight. Only the 200 and 400 mg/kg body weight extracts exhibited significant result (P <0.05) when compared with control. The rats exhibited 9.59%, 28.72% and 45.8% inhibition of granuloma mass formation after the 7 days treatment with 100, 200 and 400 mg/kg body weight of extract when compared with control (P <0.05) in cotton pellet granuloma.

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The anticancer-cytotoxic activities of isolated saponins, gymnemagenol (C ₃₀ H ₅₀ O ₄ ) from Gymnema sylvestre and dasyscyphin C (C ₂₈ H ₄₀ O ₈ ) from Eclipta prostrata leaves were tested under in vitro conditions in HeLa cells. The gymnemagenol and dayscyphin C at 50 μg/ml showed a good cytotoxic activity (63% and 52%, respectively) in HeLa cells at 48 hours with the IC50 value of 37 and 50 μg/ml, respectively. 5-Fluorouracil (5-FU), a positive control, showed 57.5 % cell death with the IC50 value of 36 μg/ml. The percentage of HeLa cell death was maximum (73%) after 96 hours with gymnemagenol, whereas dasyscyphin C showed only 53%. The isolated saponins were not toxic to Vero cells. From this study, it can be concluded that the saponins, gymnemagenol, and dayscyphin C have significant anticancer-cytotoxic activity on HeLa cells under in vitro conditions.

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Wattakaka volubilis (Family: Asclepiadaceae) has been reported to possess medicinal effects. In the present study, the dried leaf extract [methanol-water (1:1)] of W. volubilis designated as 'the extract' was evaluated for pharmacological activity in rats and mice. The anti-inflammatory activity was evaluated using acute, sub-chronic and chronic models of inflammation in rodents. The antipyretic and analgesic activities were evaluated in mice models. In the acute toxicity study, it was found that the extract was non-toxic up to 1 g/kg, i.p. The extract (50, 100 and 200 mg/kg, i.p.) was found to possess, anti-inflammatory, analgesic and antipyretic activities in a dose-dependent manner and the effect was comparable with that produced by the standard drug, ibuprofen. The extract significantly inhibited the arachidonic acid-induced paw oedema in rats, indicating that the extract inhibited both the cyclo-oxygenase and lipo-oxygenase pathways of arachidonic acid metabolism. The extract also significantly enhanced the macrophage count in mice in a dose- and time-dependent manner. It is possible that the saponins present in the extract may be responsible for these activities.

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In order to scientifically appraise some of the anecdotal, folkloric, ethno medical uses of Pisonia aculeata Linn. (Nyctaginaceae), the present study was undertaken to examine the antitumor activity of Pisonia aculeata leaves extract on Ehrlich Ascites Carcinoma (EAC) in mice. Tumor was induced in mice by intraperitoneal injection of Ehrlich Ascites Carcinoma cells (1X10 ⁶ cells/mouse). Ethanol extract of Pisonia aculeata (EEPA) was administered to the experimental animals at the doses of 250 & 500 mg/kg/day, p.o. The antitumor effect of the extract was evaluated by using survival time, hematological parameters, increase in body weight, solid tumour volume and peritoneal cell count. Oral administration of EEPA increased the survival time and inhibits the weight gain of the tumor bearing mice. After 14 days of inoculation, the extract also reduces the solid tumor volume developed by the EAC cells. The findings of this study indicate that the EEPA possesses significant antitumor activity on dose dependent manner.

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Ageratum conyzoides L. (AC) is an annual herbaceous plant with a long history of traditional medicinal uses in many countries in the world, especially in the tropical and subtropical regions. The weed has been known since ancient times for its curative properties and has been utilized for treatment of various ailments, such as burns and wounds, for antimicrobial properties, for many infectious conditions and bacterial infections, arthrosis, headaches and dyspnea, pneumonia, analgesic, anti-inflammatory, antiasthmatic, antispasmodic and haemostatic effects, stomach ailments, gynaecological diseases, leprosy and other skin diseases. A wide range of chemical compounds including alkaloids, cumarins, flavonoids, chromenes, benzofurans, sterols and terpenoids have been isolated from this species. Extracts and metabolites from this plant have been found to possess pharmacological and insecticidal activities. This contribution provides a comprehensive review of its ethnomedical uses, chemical constituents and the pharmacological profile as a medicinal plant. Particular attention has been given to analgesic and anti-inflammatory, antibacterial and wound healing properties, radioprotective, antifungal, anthelmintic and nematicidal, insecticidal effects presented in this review such that the potential use of this plant either in pharmaceutics or as an agricultural resource can be evaluated.

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Liver toxicity is a major health problem of worldwide proportions. Herbal medicines derived from plant extracts are being increasingly utilized to treat a wide variety of clinical diseases. In the present study, LIV-first (16.3 mg/kg, p.o.) was used to screen the hepatoprotective activity. Hepatotoxicity was induced in experimental animals by administration of carbon tetrachloride (CCl ₄ ) (1 ml/kg, i.p). Silymarin (25 mg/kg,p.o.) was used as the standard. Biochemical parameters like serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), alkaline phosphatase (ALP) and serum bilirubin were measured. Cytotoxicity of CCl ₄ was estimated by quantitating the release of malondialdehyde. The activity of tissue antioxidant enzymes namely superoxide dismutase, catalase and the level of total protein and glutathione were also measured. Histopathological evaluation of liver sections was also done. CCl ₄ administration in rats elevated the levels of SGPT, SGOT, ALP and bilirubin. Administration of LIV-first significantly ( P<0.01) prevented this increase. The activity of anti-oxidant enzymes in carbon tetrachloride CCl ₄ -treated group was decreased and these enzyme levels were significantly ( P<0.05) increased in LIV-first-treated groups. Histopathological studies revealed that the concurrent administration of CCl ₄ with the extract exhibited protection of the liver tissue, which further evidenced the above results. The study confirmed the hepatoprotective activity of LIV-first, which may be attributed to its antioxidant property.

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Balanites aegyptiaca is an evergreen, woody, true xerophytic tree of tremendous medicinal importance. It belongs to the family Balanitaceae and is distributed throughout the drier parts of India. B. aegyptiaca has been used in a variety of folk medicines in India and Asia. Various parts of the plant are used in Ayurvedic and other folk medicines for the treatment of different ailments such as syphilis, jaundice, liver and spleen problems, epilepsy, yellow fever and the plant also has insecticidal, antihelminthic, antifeedant, molluscicidal and contraceptive activities. Research has been carried out using different in vitro and in vivo techniques of biological evaluation to support most of these claims. This review presents the traditional uses, phytochemistry and pharmacological properties of this medicinal plant.

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Psidium guajava L, belonging to the Myrtacea family, has been reported to have anti-diarrheal, hepatoprotective, hypoglycemic, lipid lowering, antibacterial and antioxidant activities. It contains important phytoconstituents such as tannins, triterpenes, flavonoid:quercetin, pentacyclic triterpenoid:guajanoic acid, saponins, carotenoids, lectins, leucocyanidin, ellagic acid, amritoside, beta-sitosterol, uvaol, oleanolic acid and ursolic acid. In view of the immense medicinal importance of the plant, this review is an effort to compile all the information reported on its phytochemical and pharmacological activities. The present review is an attempt to generate interest among the masses regarding its immense potential in preventing and treating several common diseases.

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Hyperlipidemia is defined as increase in the lipid content (groups of fat or fat like substances along with their lipoprotein counterpart) in blood. Abundant evidence are there to proof the link between hyperlipidemia and atherosclerosis. Lagenaria siceraria commonly known as Bottle gourd, which is official in Ayurvedic Pharmacopoeia of India, and having composition of variety of essential phytoconstituents, so that the fruits are traditionally used for their cardioprotective, cardiotonic, general tonic, diuretic, aphrodisiac, antidote to certain poisons and scorpion strings, alternative purgative, and cooling effects. In the present study fruit juice was obtained by crushing the fresh fruits of L. siceraria in the juicer and was subsequently dried in the oven at 40°-50°C. The parent dried juice extract was then fractionated by using the solvents according to polarity in ascending order i.e. by using chloroform: acetic acid, methanol, pyridine, and water. Each fraction was dried in oven at 40°-50°C. Thin layer chromatography (TLC) used active fraction obtained by column chromatography for further isolation. The solvent system developed on trial and error basis was n-butanol: methaol: water (6:2:2). Four spots were obtained and were named as LSN-I, LSN-II, LSN-III and LSN-IV. Isolated spots were collected by using preparative TLC the isolated compounds were tested for Antihyperlipidemic activity and compounds LSN-I, LSN-II, LSN-III has shown significant results. The study exhibited that elevated levels of blood cholesterol, triglycerides, LDL, were significantly reduced and decreased HDL was significantly increased by the administration of fractions of L. siceraria fruit juice.

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