Wound-healing potential of aqueous and ethanolic extracts of apamarga leaves

P. K. Ghosh, V. B. Gupta, M. S. Rathore, Iqbal Hussain

Abstract


The present research work was aimed at exploring the wound-healing activity of alcoholic and an aqueous Achyranthes aspera Linn (apamarga) leaf extract. Leaf extracts (aqueous and ethanolic) were examined for its wound-healing activity in the form of ointment (1% w/w) in Excision model and Incision model in rats. The evaluation was made in terms of wound contractibility and wound closure time. A. aspera Linn leaf extract showed significant (P<0.001) wound-healing activity when compared with control and was as effective as soframycin (standard cream for comparison). The wound-healing potential of ethanolic extract was slightly more compared with aqueous extract. The present study showed the wound-healing potential of apamarga leaves.
Key words: Apamarga, extract, wound

Full Text:

PDF

References


Tahiliani P, Kar A. Achyranthes aspera elevated thyroid hormone

level and decreases hepatic lipid peroxidation in male rats. J

Ethnopharmacol 2000;71:527-32.

Pakrashi A. Abortifacient principle of Achyranthes aspera Linn.

Indian J Exp. 1977;15:856-8.

Verma DK, Singh SK, Tripathi VA. Rare antibacterial activity of

Achyranthes aspera Linn. Indian Drug 1997;34:32-5.

Rao YV, Chakrabarti R. Dietary incorporation of Achyranthes aspera

seed influences the immunity of common carp cyprinus carpio.

Indian J Animal Sci 2005;75:1097-102.

Chakraborty A, Brantner A, Mukainaka T, Nobukuni Y, Kuchide

M, Konoshima T, et al. Cancer chemopreventive activity of

Achyranthes aspera leaves on Epstein-Barr virus activation

and two-stage mouse skin carcinogenesis. Cancer Lett 2002;

:1-5.

Gokhale AB, Damre AS, Kulkarni KR, Saraf MN. Preliminary

evaluation of anti-inflammatory and anti-arthritic activity of S.

lappa, A. speciosa and A. aspera. Phytomedicine (Jena) 2002;9:

-7.

Kokate CK. Practical pharmacognosy. 4th ed. New Delhi: Vallabh

Prakasan; 2001. p. 108-10,123-4.

Mukherjee PK. Quality Control of Herbal Drugs. New Delhi:

Business Horizons; 1st ed. 2002.




DOI: http://dx.doi.org/10.22377/ijgp.v5i1.167

Refbacks

  • There are currently no refbacks.