Antibacterial evaluation of Sapindus emarginatus Vahl leaf in in-vitro conditions

Abstract

The emergence of antibiotic resistant bacterial strains is a growing problem and is an important concern for patients, physicians,healthcare managers and policymakers as it results in poorer health and economic outcomes. This has led to an urgent global call for new antimicrobial drugs, particularly from natural resources. In the present study, antibacterial evaluation of aqueous, 1, 4-dioxan, methanol and acetone extracts of Sapindus emarginatus Vahl leaf was studied against 6 medically important bacterial strains. Antibacterial assay was performed by agar well diffusion method. Gentamicin (5mg/10ml) was used as standard antibiotic for comparison. Dioxan extract exhibited potential antibacterial activity
Key words: Agar well diffusion method, antibacterial evaluation, Sapindus emarginatus